More than 900 workers were balloted after rejecting the company's final pay offer of 2.2%, and union shop stewards will be meeting this week to decide what action to take.
Industrial action could seriously disrupt the production of Pirelli Tyres, a major producer and exporter of tyres, and one of the most profitable parts of the Italian multinational Pirelli Group.
Peter Booth, T&G National Organiser for manufacturing, said: “The overwhelming vote in favour of industrial action shows the strength of feeling against the company's 2.2% final pay offer. Our members clearly feel that a below inflation pay offer does not reflect their expectations, particularly with rising prices of energy.
"We now have a strong mandate for action and the stewards will meet this week to determine the nature of that action. We have today informed the company of the ballot result and urge them to reconsider."
482 members of the manual workers (66.4%) voted in favour of industrial action, 244 (33.6%) voted against, on a turnout of 730 (78.2%). 569 (78.2%) voted in favour of action short of a strike, and 159 (21.8%) against.
The members are based in Carlisle and Burton-on-Trent. The other trade union at Pirelli is Amicus, representing around 200 members, who is also balloting members for industrial action.